Birth Defects with the Use of Valproate: An Impact on the Prescribing Pattern amongst the Health Care Professionals in India

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Dr V KALAISELVAN
Dr NISHITH KESERWANI
Dr RISHI KUMAR
Dr RAJEEV SINGH RAGHUVANSHI
Dr KRISHNAMURTHY B

Abstract

Objective: The present study was carried out to evaluate the impact of Pharmacovigilance Programme of India (PvPI) initiative
to reduce the use of sodium valproate/valproic acid (SV/VA) in the women of childbearing age group. Methods: In our
questionnaire-based study, 251 health care professionals (HCPs) participated from 41 medical colleges across India, which are
also working as Adverse drug reaction Monitoring Centres (AMCs) under PvPI. Results: The data collected at the National
Coordination Centre (NCC) shows the significant decrease in the use of SV/VA in the women of childbearing age group after
the PvPI initiative on Information, Education, and Communication (IEC) materials for HCPs. However, it was found that
40% of HCPs of Gynecology and Neurology Department were still not aware of the initiative taken by the Government of
India to reduce the use of SV/VA in the women of childbearing age group. Conclusion: PvPI, therefore, needs to take more
measures to increase the reach of their resource materials to all HCPs.

Article Details

Section

Clinical Study

How to Cite

Birth Defects with the Use of Valproate: An Impact on the Prescribing Pattern amongst the Health Care Professionals in India. (2024). Indian Journal Of Clinical Practice, 35(1), 20-27. https://doi.org/10.59793/ijcp.v35i1.1030

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