Rare Adverse Effect of a Commonly Used Drug in Chronic Kidney Disease

Abstract

Chronic kidney disease (CKD) and hypertension can lead to each other. Majority of the patients with CKD have hypertension.
Sympathetic overactivity has been suggested as one of the important etiologies of hypertension in CKD patients. Clonidine is
used as a central sympatholytic to control hypertension in CKD patients. Drug-induced sialadenitis has been reported with
multiple drugs including antihypertensives. We report a case of clonidine-induced sialadenitis, which has been rarely seen
despite the widespread use of this drug among CKD patients requiring multiple antihypertensive drugs.