A Comparative Study to Analyze the Association of Metabolic Syndrome in Females with Diagnosed Polycystic Ovarian Syndrome

Abstract

Objectives: Polycystic ovarian syndrome (PCOS) is a common female endocrinopathy affecting 5-6% of women within the age
group 12-45 years. This study was contemplated with the aim to study the prevalence of metabolic syndrome in patients of
PCOS and to study the spectrum of clinical features of metabolic syndrome in patients of PCOS. Material and methods: This
case-controlled study was conducted on 50 cases of diagnosed PCOS females and compared with 50 healthy age and body
mass index (BMI) matched controls. Results: The prevalence of metabolic syndrome in PCOS patients was found to be 24%
and in control group it was 6%. Among patients with metabolic syndrome 14% of patients had high blood pressure, 12% had
impaired fasting glucose, 38% had high waist-hip ratio, 14% had raised serum triglycerides and 44% had decreased high-density
lipoprotein (HDL). Conclusion: It is observed that metabolic syndrome manifests at an early age in women with PCOS. In order
to prevent metabolic syndrome one should maintain BMI <25 and waist circumference <35 inches.