The Mind and Body are Connected with Each Other Through Psychoneuroendocrine and Reticuloendothelial System

Abstract

Psychoneuroendocrinoimmunology (PNEI) is the study of the interaction between psychological, neural, endocrine and
immunological responses, which was first described in 1936. There is a unity of mind and body (reflected in term mind and
body medicine); and psychological factors must be taken into account when considering all disease states. Although most
physical disorders are influenced by stress, conflict or generalized anxiety, some disorders are more affected than others. The
concept of PNEI system propose that stressful event triggers cognitive and affective responses which, in turn induce sympathetic
nervous system and endocrine changes and these ultimately impair immune function. The present review provides an overview
of the fundamental literature on PNEI and its interaction with chronic low-grade cellular inflammation processes, hormetic
processes, longevity with reference to resilience as a key factor in natural/pathologic evolution of aging. And consequently
with the homoeopathic standpoint where dynamic, functional and structural plane been correlated.