The Effect of Phototherapy on Various Biochemical Parameters in Neonatal Hyperbilirubinemia

Dr SHASHI KANT MEENA; Dr JAGDISH SINGH; Dr DHAN RAJ BAGRI; Dr NEHA AGRAWAL

doi:10.59793/ijcp.v34i6.714

The Effect of Phototherapy on Various Biochemical Parameters in Neonatal Hyperbilirubinemia

Authors

Dr SHASHI KANT MEENA Senior Registrar, Dept. of Pediatrics, SMS Medical College, Jaipur, Rajasthan, India
Dr JAGDISH SINGH Senior Professor, Dept. of Pediatrics, SMS Medical College, Jaipur, Rajasthan, India
Dr DHAN RAJ BAGRI Assistant Professor , Sir Padampat Institute of Neonatology and Child Health (J K Lon Hospital) and SMS Medical College, Jaipur, Rajasthan, India
Dr NEHA AGRAWAL Associate Professor , Dept. of Pediatrics, SMS Medical College, Jaipur, Rajasthan, India

DOI:

https://doi.org/10.59793/ijcp.v34i6.714

Keywords:

Phototherapy,, neonatal hyperbilirubinemia,, neonatal hypocalcemia,, biochemical parameters in neonates

Abstract

Phototherapy (PT) is the current modality of choice for treatment of unconjugated hyperbilirubinemia. The effects of PT on
various biochemical parameters including serum calcium, bilirubin profile, serum total protein, albumin, urea, creatinine,
serum electrolytes in neonates are a concern in current times. Like any other treatment, PT also has its own side effects.
This hospital-based, prospective, comparative observational study was conducted with the objective to assess the level of
various biochemical parameters like serum calcium, serum sodium, serum potassium, serum chloride, serum urea and serum
creatinine, serum total protein and serum albumin in addition to serum bilirubin before PT and after completion of 48 hours
of PT in full-term neonates with unconjugated hyperbilirubinemia at a tertiary care center. On comparing biochemical
parameters, a statistically significant difference in parameters such as bilirubin, urea, creatinine, sodium, potassium, chloride,
calcium, total protein and albumin was observed after PT. On the other hand, there was a statistically nonsignificant difference
in corrected calcium (p = 0.945).

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Published

2023-11-14

Issue

Vol. 34 No. 6 (2023)

Section

Clinical Study

License

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How to Cite

The Effect of Phototherapy on Various Biochemical Parameters in Neonatal Hyperbilirubinemia. (2023). Indian Journal Of Clinical Practice, 34(6), 16-25. https://doi.org/10.59793/ijcp.v34i6.714