Disseminated Trichosporonosis Presenting with Acute Emphysematous Pyelonephritis in Severely Comorbid Patient
Keywords:
Trichosporonosis, emphysematous pyelonephritis, antifungal, voriconazoleAbstract
Trichosporon asahii is a basidiomycetous yeast, which is a rare and life-threatening pathogen and is invariably associated
with disseminated trichosporonosis. Presented here is the report of a successfully treated case of a 74-year-old female with
disseminated trichosporonosis who presented with acute emphysematous pyelonephritis complicated with septic plus
cardiogenic shock and septic acute renal failure and heart failure stage ‘C’ with ischemic heart disease, diabetes mellitus
type 2, hypertension. She was admitted in our hospital with complaints of high-grade fever, abdominal pain, nausea,
vomiting, giddiness, burning micturition, difficulty in breathing since 1 week. CT scan KUB showed acute emphysematous
pyelonephritis and blood culture and urine culture showed growth of T. asahii. Antifungal susceptibility testing was done
and the pathogen was found sensitive to voriconazole, fluconazole and amphotericin B. Patient responded well to intravenous
voriconazole and improved completely in such severely comorbid condition. Disseminated trichosporonosis is a very rare
disease with mortality rate as high as 70%, especially in severely comorbid patient.
Downloads
Published
Issue
Section
License
All open access articles published in IJCP are distributed under the terms of the CC BY-NC 4.0 license (Creative Commons Attribution-Non-Commercial 4.0 International Public License). This license permits unrestricted use, distribution, and reproduction of the articles in any medium for non-commercial purposes, provided that: The original authorship is properly and fully attributed. The IJCP is cited as the original place of publication with correct citation details. If an original work is reproduced or disseminated in part or as a derivative work, this must be clearly indicated. No articles are reproduced for commercial use without prior consent from the IJCP. All licensing requests and permissions for commercial use will be managed by the Publisher.
