Dermato-Metabolic Syndrome

Abstract

We define the term ‘dermato-metabolic syndrome’ as the dermatologic (skin, hair, and nail) conditions associated with
metabolic syndrome. These abnormalities can be classified as metabolic (hyperinsulinism, hyperandrogenism, hyperuricemia),
mechanical (involvement of epidermal, dermal, sebaceous and sweat glands, subcutaneous tissue), mitogenic, miasmatic
(infections) and microvascular/venous insufficiency. This construct highlights the importance of skin, and its related
appendages, as a site of target organ damage in metabolic syndrome. The concept underscores the need for team-based
approach towards dermato-vigilance in metabolic patients, metabolic vigilance in dermatologic patients, and management
of both dermatological and metabolic manifestations of dermo-metabolic syndrome.