Is It Structural or Metabolic? A Diagnostic Dilemma

Main Article Content

Dr E Sumanraj
Dr N Vijayakumar
Dr A Nanjilkumaran
Dr R Umarani

Abstract

Osmotic demyelination syndrome (ODS), a disease affecting chronic alcoholic and malnourished
patients was described by Adams and colleagues in 1959. It is also known as pontine
myelinolysis. Pontine myelinolysis can be subdivided into central pontine myelinolysis (CPM)
and extrapontine myelinolysis (EPM) depending upon the level of demyelination, within the
pons or outside the pons, respectively. Rapid correction of hyponatremia contributes to the
pathogenesis of ODS. Whenever a chronic alcoholic and/or malnourished develops confusion,
quadriplegia, pseudobulbar palsy and pseudocoma (Locked-in-syndrome) over a period of
several days, a high index of suspicion for ODS must be held

Article Details

Section

Case Report

How to Cite

Is It Structural or Metabolic? A Diagnostic Dilemma. (2024). Indian Journal Of Clinical Practice, 24(4), 33-35. https://doi.org/10.59793/ijcp.v24i4.969

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