Narrative Review of Nimesulide in Adults: Current Scenario

Authors

  • Shriram V Kulkarni Senior Consultant, Internal Medicine, Navi Mumbai, Maharashtra
  • Jawed Ahmed Consultant, Family Medicine, Vivekananda Polyclinic and IMS, Lucknow, Uttar Pradesh
  • Mahi Pal Consultant, Dept. of Medicine, Amar Jyoti Medicare, Patna, Bihar
  • Binod Kumar Dharewa Consultant, Dept. of Medicine, SN Medical College, Jodhpur, Rajasthan
  • Vikram Veer Consultant, Dept. of Medicine, SN Medical College, Jodhpur, Rajasthan
  • Anup Uttam Petare Medical Affairs, Dr Reddy’s Laboratories Limited, Hyderabad, Telangana #7-1-27, Ameerpet, Hyderabad - 500 016, Telangana
  • Krishna Chaitanya Veligandla Consultant, Dept. of Orthopedics, Veer Hospital, Patna, Bihar

Keywords:

COX-2 inhibitor, fever, inflammation, NSAID, pain

Abstract

Nimesulide, a nonsteroidal anti-inflammatory drug (NSAID), has been used as an effective treatment regimen for patients aged >12 years for fever, acute pain, acute tendinitis, osteoarthritis and dysmenorrhea. It is reported to be a superior antipyretic and anti-inflammatory drug than paracetamol and aspirin, respectively, and is equal to any of the NSAIDs alone in terms of analgesia. This paper reviews the current scenario of nimesulide in adult patients, concerning clinical evidence, use in special population and expert opinion. Overall, in comparison to other NSAIDs, including coxibs, nimesulide has a promising overall efficacy, safety and tolerability profile, as well as a satisfactory benefit/risk evaluation.

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Published

2022-12-13

Issue

Vol. 33 No. 5 (2022)

Section

Review Article

License

All open access articles published in IJCP are distributed under the terms of the CC BY-NC 4.0 license (Creative Commons Attribution-Non-Commercial 4.0 International Public License). This license permits unrestricted use, distribution, and reproduction of the articles in any medium for non-commercial purposes, provided that:  The original authorship is properly and fully attributed.   The IJCP is cited as the original place of publication with correct citation details.  If an original work is reproduced or disseminated in part or as a derivative work, this must be clearly indicated.  No articles are reproduced for commercial use without prior consent from the IJCP. All licensing requests and permissions for commercial use will be managed by the Publisher. 

How to Cite

Narrative Review of Nimesulide in Adults: Current Scenario. (2022). Indian Journal Of Clinical Practice, 33(5), 13-20. https://ojs.ijcp.in/index.php/IJCP/article/view/306

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